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(-) Description

Title :  CRAMBIN MIXED SEQUENCE FORM AT 180 K. PROTEIN/WATER SUBSTATES
 
Authors :  M. M. Teeter, A. Yamano, B. Stec, U. Mohanty
Date :  10 Sep 01  (Deposition) - 31 Oct 01  (Release) - 05 Feb 14  (Revision)
Method :  X-RAY DIFFRACTION
Resolution :  0.89
Chains :  Asym./Biol. Unit :  A
Keywords :  Water, Substate, Function, Plant Protein (Keyword Search: [Gene Ontology, PubMed, Web (Google)] )
 
Reference :  M. M. Teeter, A. Yamano, B. Stec, U. Mohanty
On The Nature Of A Glassy State Of Matter In A Hydrated Protein: Relation To Protein Function.
Proc. Natl. Acad. Sci. Usa V. 98 11242 2001
PubMed-ID: 11572978  |  Reference-DOI: 10.1073/PNAS.201404398

(-) Compounds

Molecule 1 - CRAMBIN
    Chains: A
    Organism Scientific: CRAMBE HISPANICA SUBSP. ABYSSINICA
    Organism Taxid: 3721
    Strain: SUBSP. ABYSSINICA

 Structural Features

(-) Chains, Units

  1
Asymmetric/Biological Unit : A

Summary Information (see also Sequences/Alignments below)

(-) Ligands, Modified Residues, Ions  (1, 1)

Asymmetric/Biological Unit (1, 1)
No.NameCountTypeFull Name
1EOH1Ligand/IonETHANOL

(-) Sites  (1, 1)

Asymmetric Unit (1, 1)
No.NameEvidenceResiduesDescription
1AC1SOFTWAREILE A:7 , ASN A:46BINDING SITE FOR RESIDUE EOH A 66

(-) SS Bonds  (3, 3)

Asymmetric/Biological Unit
No.Residues
1A:3 -A:40
2A:4 -A:32
3A:16 -A:26

(-) Cis Peptide Bonds  (0, 0)

(no "Cis Peptide Bond" information available for 1JXW)

 Sequence-Structure Mapping

(-) SAPs(SNPs)/Variants  (2, 2)

Asymmetric/Biological Unit (2, 2)
  dbSNPPDB
No.SourceVariant IDVariantUniProt IDStatusIDChainVariant
1UniProtVAR_CRAM_CRAAB_001 *P22SCRAM_CRAAB  ---  ---AP22S
2UniProtVAR_CRAM_CRAAB_002 *L25ICRAM_CRAAB  ---  ---AL25I
   * ID not provided by source
  SNP/SAP Summary Statistics (UniProtKB/Swiss-Prot)

(-) PROSITE Motifs  (1, 1)

Asymmetric/Biological Unit (1, 1)
 PROSITEUniProtKBPDB
No.IDACDescriptionIDLocationCountLocation
1THIONINPS00271 Plant thionins signature.CRAM_CRAAB3-16  1A:3-16

(-) Exons   (0, 0)

(no "Exon" information available for 1JXW)

(-) Sequences/Alignments

Asymmetric/Biological Unit
   Reformat: Number of residues per line =  ('0' or empty: single-line sequence representation)
  Number of residues per labelling interval =   
  UniProt sequence: complete  aligned part    
   Show mapping: SCOP domains CATH domains Pfam domains Secondary structure (by author)
SAPs(SNPs) PROSITE motifs Exons
(details for a mapped element are shown in a popup box when the mouse pointer rests over it) 
Chain A from PDB  Type:PROTEIN  Length:48
 aligned with CRAM_CRAAB | P01542 from UniProtKB/Swiss-Prot  Length:46

    Alignment length:48
                                                     25                     
                                                   24 |                     
                                                 22 | |                     
                                               21 | | |                     
                                    10        20| | | | 28        38        
            CRAM_CRAAB    1 TTCCPSIVARSNFNVCRLPGT-PEA-LCATYTGCIIIPGATCPGDYAN 46
               SCOP domains d1jxwa_ A: Crambin                               SCOP domains
               CATH domains 1jxwA00 A:1-46                                   CATH domains
               Pfam domains ------------------------------------------------ Pfam domains
         Sec.struct. author .ee..hhhhhhhhhhhhh...hhhhhhhhhhhh.ee............ Sec.struct. author
                 SAPs(SNPs) ---------------------SS--II--------------------- SAPs(SNPs)
                    PROSITE --THIONIN       -------------------------------- PROSITE
                 Transcript ------------------------------------------------ Transcript
                  1jxw A  1 TTCCPSIVARSNFNVCRLPGTSPEAILCATYTGCIIIPGATCPGDYAN 46
                                    10        20        28        38
   Legend:   → Mismatch (orange background)
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  x → Chemical Group (purple background, 'x', labelled with number + name, e.g. ACE or NH2)
  extra numbering lines below/above indicate numbering irregularities and modified residue names etc., number ends below/above '|'

 Classification and Annotation

(-) SCOP Domains  (1, 1)

Asymmetric/Biological Unit
(-)
Class: Small proteins (3458)

(-) CATH Domains  (1, 1)

Asymmetric/Biological Unit
(-)
Class: Alpha Beta (26913)

(-) Pfam Domains  (0, 0)

(no "Pfam Domain" information available for 1JXW)

(-) Gene Ontology  (2, 2)

Asymmetric/Biological Unit(hide GO term definitions)
Chain A   (CRAM_CRAAB | P01542)
biological process
    GO:0006952    defense response    Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
cellular component
    GO:0005576    extracellular region    The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

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  1jxw
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 Related Entries

(-) Entries Sharing at Least One Protein Chain (UniProt ID)

UniProtKB/Swiss-Prot
        CRAM_CRAAB | P01542: 1ab1 1cbn 1ccm 1ccn 1cnr 1crn 1cxr 1ejg 1jxt 1jxu 1jxx 1jxy 1yv8 1yva 2eya 2eyb 2eyc 2eyd 2fd7 2fd9 3nir 3u7t 3ue7 4fc1

(-) Related Entries Specified in the PDB File

1ab1 1AB1 IS CRAMBIN PURE SER22/ILE25 ISOFORM AT 150 K
1cbn 1CBN IS CRAMBIN MIXED SEQUENCE ISOFORM AT 130 K AND 0.83 A
1cnr 1CNR IS CRAMBIN PURE PRO22/LEU25 ISOFORM AT 150 K
1crn 1CRN IS CRAMBIN MIXED SEQUENCE ISOFORM AT 293 K
1ejg 1EJG IS CRAMBIN MIXED SEQUENCE ISOFORM AT 100 K AND 0.54 A
1jxt 1JXT IS MIXED SEQUENCE ISOFORM OF CRAMBIN AT 160 K, THE SAME CRYSTAL.
1jxu 1JXU IS MIXED SEQUENCE ISOFORM OF CRAMBIN AT 240 K, THE SAME CRYSTAL.
1jxx 1JXX IS MIXED SEQUENCE ISOFORM OF CRAMBIN AT 200 K, THE SAME CRYSTAL.
1jxy 1JXY IS MIXED SEQUENCE ISOFORM OF CRAMBIN AT 220 K, THE SAME CRYSTAL.