| molecular function |
|---|
| | GO:0005515 | | protein binding | | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
| biological process |
|---|
| | GO:0007015 | | actin filament organization | | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. |
| | GO:0030154 | | cell differentiation | | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| | GO:0007275 | | multicellular organism development | | The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
| | GO:0050771 | | negative regulation of axonogenesis | | Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. |
| | GO:0007399 | | nervous system development | | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
| | GO:0045773 | | positive regulation of axon extension | | Any process that activates or increases the frequency, rate or extent of axon extension. |
| | GO:0050772 | | positive regulation of axonogenesis | | Any process that activates or increases the frequency, rate or extent of axonogenesis. |
| | GO:0030335 | | positive regulation of cell migration | | Any process that activates or increases the frequency, rate or extent of cell migration. |
| | GO:0090316 | | positive regulation of intracellular protein transport | | Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. |
| | GO:0050770 | | regulation of axonogenesis | | Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. |
| | GO:2000114 | | regulation of establishment of cell polarity | | Any process that modulates the frequency, rate or extent of establishment of cell polarity. |
| cellular component |
|---|
| | GO:0030424 | | axon | | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. |
| | GO:0030054 | | cell junction | | A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. |
| | GO:0042995 | | cell projection | | A prolongation or process extending from a cell, e.g. a flagellum or axon. |
| | GO:0005737 | | cytoplasm | | All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| | GO:0030425 | | dendrite | | A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. |
| | GO:0012505 | | endomembrane system | | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
| | GO:0030175 | | filopodium | | Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. |
| | GO:0030426 | | growth cone | | The migrating motile tip of a growing nerve cell axon or dendrite. |
| | GO:0071437 | | invadopodium | | A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate. |
| | GO:0030027 | | lamellipodium | | A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments. |
| | GO:0016020 | | membrane | | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| | GO:0043025 | | neuronal cell body | | The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. |
| | GO:0043204 | | perikaryon | | The portion of the cell soma (neuronal cell body) that excludes the nucleus. |
Description
