molecular function |
| GO:0003861 | | 3-isopropylmalate dehydratase activity | | Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O. |
| GO:0016829 | | lyase activity | | Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. |
biological process |
| GO:0009082 | | branched-chain amino acid biosynthetic process | | The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. |
| GO:0008652 | | cellular amino acid biosynthetic process | | The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. |
| GO:0009098 | | leucine biosynthetic process | | The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid. |
| GO:0008152 | | metabolic process | | The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
cellular component |
| GO:0009316 | | 3-isopropylmalate dehydratase complex | | A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. |