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(-) Description

Title :  NMR STRUCTURE FOR A 3-STRANDED PARALLEL BETA-SHEET
 
Authors :  V. M. Kung, G. Cornilescu, S. H. Gellman
Date :  24 Jun 15  (Deposition) - 28 Oct 15  (Release) - 03 Feb 16  (Revision)
Method :  SOLUTION NMR
Resolution :  NOT APPLICABLE
Chains :  NMR Structure  :  A  (10x)
NMR Structure *:  A  (1x)
Keywords :  De Novo Protein (Keyword Search: [Gene Ontology, PubMed, Web (Google))
 
Reference :  V. M. Kung, G. Cornilescu, S. H. Gellman
Impact Of Strand Number On Parallel Beta-Sheet Stability.
Angew. Chem. Int. Ed. Engl. V. 54 14336 2015
PubMed-ID: 26457984  |  Reference-DOI: 10.1002/ANIE.201506448

(-) Compounds

Molecule 1 - DESIGNED BETA SHEET
    ChainsA
    EngineeredYES
    Organism ScientificSYNTHETIC CONSTRUCT
    Organism Taxid32630
    SyntheticYES

 Structural Features

(-) Chains, Units

  1
NMR Structure (10x)A
NMR Structure * (1x)A

Summary Information (see also Sequences/Alignments below)

(-) Ligands, Modified Residues, Ions  (5, 5)

NMR Structure (5, 5)
No.NameCountTypeFull Name
14FU1Mod. Amino Acid(1R,2S)-CYCLOHEXANE-1,2-DICARBOXYLIC ACID
24G61Mod. Amino Acid2-METHYLPROPANE-1,2-DIAMINE
3ACE1Mod. Amino AcidACETYL GROUP
4DPR1Mod. Amino AcidD-PROLINE
5NH21Mod. Amino AcidAMINO GROUP
NMR Structure * (5, 5)
No.NameCountTypeFull Name
14FU1Mod. Amino Acid(1R,2S)-CYCLOHEXANE-1,2-DICARBOXYLIC ACID
24G61Mod. Amino Acid2-METHYLPROPANE-1,2-DIAMINE
3ACE1Mod. Amino AcidACETYL GROUP
4DPR1Mod. Amino AcidD-PROLINE
5NH21Mod. Amino AcidAMINO GROUP

(-) Sites  (1, 1)

NMR Structure (1, 1)
No.NameEvidenceResiduesDescription
1AC1SOFTWARE4G6 A:7 , VAL A:9 , LYS A:23 , NH2 A:24BINDING SITE FOR RESIDUE DPR A 8

(-) SS Bonds  (0, 0)

(no "SS Bond" information available for 2N4N)

(-) Cis Peptide Bonds  (0, 0)

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 Sequence-Structure Mapping

(-) SAPs(SNPs)/Variants  (0, 0)

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(-) PROSITE Motifs  (0, 0)

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(-) Exons   (0, 0)

(no "Exon" information available for 2N4N)

(-) Sequences/Alignments

NMR Structure
   Reformat: Number of residues per line =  ('0' or empty: single-line sequence representation)
  Number of residues per labelling interval =   
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Chain A from PDB  Type:PROTEIN  Length:25
                                                        
               SCOP domains ------------------------- SCOP domains
               CATH domains ------------------------- CATH domains
               Pfam domains ------------------------- Pfam domains
         Sec.struct. author ......................... Sec.struct. author
                 SAPs(SNPs) ------------------------- SAPs(SNPs)
                    PROSITE ------------------------- PROSITE
                 Transcript ------------------------- Transcript
                  2n4n A  0 xERFYEKxxVQKFIRVxGVTIREKx 24
                            |      ||9      | 19    |
                            |      7-4G6   16-4FU  24-NH2
                            0-ACE   8-DPR            

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 Classification and Annotation

(-) SCOP Domains  (0, 0)

(no "SCOP Domain" information available for 2N4N)

(-) CATH Domains  (0, 0)

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(-) Pfam Domains  (0, 0)

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(-) Gene Ontology  (0, 0)

NMR Structure(hide GO term definitions)
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