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(-) Description

Title :  CRYSTAL STRUCTURE OF OVINE SERUM ALBUMIN
 
Authors :  A. Bujacz, J. A. Talaj, A. J. Pietrzyk, G. Bujacz
Date :  25 Jul 13  (Deposition) - 17 Sep 14  (Release) - 17 Sep 14  (Revision)
Method :  X-RAY DIFFRACTION
Resolution :  2.30
Chains :  Asym./Biol. Unit :  A
Keywords :  Helical Structure, Transport, Fatty Acids, Metabolites, Transport Protein (Keyword Search: [Gene Ontology, PubMed, Web (Google)] )
 
Reference :  A. Bujacz, J. A. Talaj, A. J. Pietrzyk
Crystal Structure Of Ovine Serum Albumin And Its Complex With 3, 5-Diiodosalicylic Acid
To Be Published
PubMed: search

(-) Compounds

Molecule 1 - SERUM ALBUMIN
    Chains: A
    Fragment: MATURE FORM OF OVINE SERUM ALBUMIN
    Organism Common: DOMESTIC SHEEP,LAMBS,WILD SHEEP
    Organism Scientific: OVIS ARIES
    Organism Taxid: 9940

 Structural Features

(-) Chains, Units

  1
Asymmetric/Biological Unit : A

Summary Information (see also Sequences/Alignments below)

(-) Ligands, Modified Residues, Ions  (6, 11)

Asymmetric/Biological Unit (6, 11)
No.NameCountTypeFull Name
12Q53Ligand/Ion(2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-HYDROXYPROPYL]OXY}PROPYL]OXY}PROPYL]OXY}PROPAN-1-OL
2ACT1Ligand/IonACETATE ION
3FMT1Ligand/IonFORMIC ACID
4LMR1Ligand/Ion(2S)-2-HYDROXYBUTANEDIOIC ACID
5MLI2Ligand/IonMALONATE ION
6SIN3Ligand/IonSUCCINIC ACID

(-) Sites  (11, 11)

Asymmetric Unit (11, 11)
No.NameEvidenceResiduesDescription
01AC1SOFTWAREGLU A:17 , LYS A:131 , TRP A:134 , ALA A:157 , ASN A:158BINDING SITE FOR RESIDUE 2Q5 A 601
02AC2SOFTWARELEU A:346 , MLI A:607BINDING SITE FOR RESIDUE 2Q5 A 602
03AC3SOFTWARETYR A:149 , ARG A:198 , SER A:214 , ARG A:217 , ARG A:256 , ILE A:289 , HOH A:800 , HOH A:801 , HOH A:868 , HOH A:876BINDING SITE FOR RESIDUE 2Q5 A 603
04AC4SOFTWARELEU A:122 , PHE A:133 , LYS A:136 , TYR A:137 , SIN A:610 , HOH A:890BINDING SITE FOR RESIDUE LMR A 604
05AC5SOFTWAREHIS A:67 , GLY A:247 , ASP A:248 , LEU A:249 , LEU A:250 , HOH A:853BINDING SITE FOR RESIDUE ACT A 605
06AC6SOFTWARELEU A:304 , TYR A:333 , HIS A:337 , TYR A:340 , LYS A:377 , HIS A:509 , HOH A:808 , HOH A:821BINDING SITE FOR RESIDUE MLI A 606
07AC7SOFTWAREPHE A:205 , LYS A:350 , SER A:479 , LEU A:480 , VAL A:481 , 2Q5 A:602BINDING SITE FOR RESIDUE MLI A 607
08AC8SOFTWAREASN A:390 , ARG A:409 , TYR A:410 , HOH A:834 , HOH A:845BINDING SITE FOR RESIDUE SIN A 608
09AC9SOFTWAREGLU A:424 , SER A:428 , ARG A:458BINDING SITE FOR RESIDUE SIN A 609
10BC1SOFTWARETYR A:137 , HIS A:145 , ARG A:185 , LMR A:604 , HOH A:890BINDING SITE FOR RESIDUE SIN A 610
11BC2SOFTWARESER A:418 , THR A:421BINDING SITE FOR RESIDUE FMT A 611

(-) SS Bonds  (17, 17)

Asymmetric/Biological Unit
No.Residues
1A:62 -A:53
2A:91 -A:75
3A:101 -A:90
4A:168 -A:123
5A:176 -A:167
6A:245 -A:199
7A:252 -A:244
8A:278 -A:264
9A:288 -A:277
10A:360 -A:315
11A:368 -A:359
12A:437 -A:391
13A:447 -A:436
14A:476 -A:460
15A:486 -A:475
16A:558 -A:513
17A:566 -A:557

(-) Cis Peptide Bonds  (1, 1)

Asymmetric/Biological Unit
No.Residues
1Glu A:95 -Pro A:96

 Sequence-Structure Mapping

(-) SAPs(SNPs)/Variants  (0, 0)

(no "SAP(SNP)/Variant" information available for 4LUF)

(-) PROSITE Motifs  (0, 0)

(no "PROSITE Motif" information available for 4LUF)

(-) Exons   (0, 0)

(no "Exon" information available for 4LUF)

(-) Sequences/Alignments

Asymmetric/Biological Unit
   Reformat: Number of residues per line =  ('0' or empty: single-line sequence representation)
  Number of residues per labelling interval =   
  UniProt sequence: complete  aligned part    
   Show mapping: SCOP domains CATH domains Pfam domains Secondary structure (by author)
SAPs(SNPs) PROSITE motifs Exons
(details for a mapped element are shown in a popup box when the mouse pointer rests over it) 
Chain A from PDB  Type:PROTEIN  Length:583
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
               SCOP domains ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SCOP domains
               CATH domains ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CATH domains
               Pfam domains ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pfam domains
         Sec.struct. author hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhhhh........hhhhhhhhhhhh..hhhhhhhhhhhhhhh..hhhhhhhhhh............hhhhhhhhhhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhhh.hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh.hhhhhhhhhhhh..........hhhhhhh...hhhhhhhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhhhh.hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhh..hhhhhhhhhhhhhhhhhhhhhhhhhhh..hhhhhhhhhh...hhhhhhhhh...........hhhhhh.hhhhh..hhhhhhhhhhhhhhhhhhhh...hhhhhhhhhhhhhhhhhhhhh..hhhhhhhhhhhhhhhhhhhhhh Sec.struct. author
                 SAPs(SNPs) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- SAPs(SNPs)
                    PROSITE ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- PROSITE
                 Transcript ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Transcript
                 4luf A   1 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 583
                                    10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580
   Legend:   → Mismatch (orange background)
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  extra numbering lines below/above indicate numbering irregularities and modified residue names etc., number ends below/above '|'

 Classification and Annotation

(-) SCOP Domains  (0, 0)

(no "SCOP Domain" information available for 4LUF)

(-) CATH Domains  (0, 0)

(no "CATH Domain" information available for 4LUF)

(-) Pfam Domains  (0, 0)

(no "Pfam Domain" information available for 4LUF)

(-) Gene Ontology  (5, 5)

Asymmetric/Biological Unit(hide GO term definitions)

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    Glu A:95 - Pro A:96   [ RasMol ]  
 

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  4luf
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 Related Entries

(-) Entries Sharing at Least One Protein Chain (UniProt ID)

UniProtKB/Swiss-Prot
        ALBU_SHEEP | P14639: 4luh

(-) Related Entries Specified in the PDB File

1ao6 HUMAN SERUM ALBUMIN
4f5s BOVINE SERUM ALBUMIN
4f5u EQUINE SERUM ALBUMIN
4f5v LEPORINE SERUM ALBUMIN
4luh