Three-Dimensional Structures of Peptaibols 

Zervamicin IIb

Sequence:

Ac TRP01 ILE02 GLN03 IVA04 ILE05 THR06 AIB07 LEU08 AIB09 HYP10

GLN11 AIB12 HYP13 AIB14 PRO15 PHE16 ol - - -

Structural Information (NMR structure, 20 models, isotropic solvent):

  • PDB file (PDB code: 1DLZ)
  • JenaLib atlas page (offers access to PDB, PDBSUM, OCA, MMDB, ... and a variety of visualizations)
  • Bending analysis
    • Methods
    • 2D bending graph [PDF]
    • 3D structure (grey sticks, Calpa: balls) with 3D curvilinear (green balls) and straight axes (red stick)
      • model 15
        • backbone structure
        • complete structure
          • still images [screen size (mono | stereo)]
          • RASMOL | CHIME [in CHIME the axes can only be displayed as balls]
    • Approximate bending angle: 51 -53° (model 17); 44-46° (model 15); 35-37° (model 6); the other models have bending angles in between.; [read Methods section for a critical assessment of bending angle determination and see a Table with a compilation of bending angles for all structures]
    • Comparative bending analysis of peptaibols

Reference:

Balashova TA, Shenkarev ZO, Tagaev AA, Ovchinnikova TV, Raap J, Arseniev AS.
FEBS Lett. 2000 , 466, 333-336.
NMR structure of the channel-former zervamicin IIB in isotropic solvents.


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