Three-Dimensional Structures of Peptaibols 

Antiamoebin I

Sequence:

Ac PHE01 AIB02 AIB03 AIB04 IVA05 GLY06 LEU07 AIB08 AIB09 HYP10
GLN11 IVA12 HYP13 AIB14 PRO15 PHE16 ol - - -

Structural Information [X-ray structure, resolution 1.4 Å, 2 chains: A(brown), B(green)]:

  • PDB file (PDB code: 1JOH)
  • JenaLib atlas page (offers access to PDB, PDBSUM, OCA, MMDB, ... and a variety of visualizations)
  • Bending analysis
    • Methods
    • 2D bending graph (chain A only) [PDF]
    • 3D structure (grey sticks, Calpa: balls) with 3D curvilinear (green balls) and straight axes (red stick)
      • chain A
      • chain B
        • backbone structure
          • no straight line-axis (RASMOL | CHIME) [in CHIME the axes can only be displayed as balls]
    • Approximate bending angle: 40-49 ° (chain A) [read Methods section for a critical assessment of bending angle determination and see a Table with bending angles for all structures)
    • Comparative bending analysis of peptaibols

Reference:

Snook CF, Woolley GA, Oliva G, Pattabhi V, Wood SF, Blundell TL, Wallace BA.
Structure 1998, 6, 783-792.
The structure and function of antiamoebin I, a proline-rich membrane-active polypeptide
.


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