Three-Dimensional Structures of Peptaibols 

Trichotoxin A50_E

Sequence:

Ac AIB01 GLY02 AIB03 LEU04 AIB05 GLN06 AIB07 AIB08 AIB09 ALA10

ALA11 AIB12 PRO13 LEU14 AIB15 AIB16 GLN17 VAL18 ol -

Structural Information (X ray structure, 2 chains, resolution: 0.90 Å):

  • PDB file (PDB code: 1M24)
  • JenaLib atlas page (offers access to PDB, PDBSUM, OCA, MMDB, ... and a variety of visualizations)
  • Bending analysis
    • Methods
    • 2D bending graph [PDF]
    • 3D structure (grey sticks, Calpa: balls) with 3D curvilinear (green balls) and straight axes (red stick)
      • chain A
        • backbone structure
        • complete structure
          • RASMOL | CHIME [in CHIME the axes can only be displayed as balls]
      • chain B
        • backbone structure
        • complete structure
          • still images [screen size (mono | stereo)]
          • RASMOL | CHIME [in CHIME the axes can only be displayed as balls]
    • Approximate bending angle: 34-36° (chain A); 32-34° (chain B); [read Methods section for a critical assessment of bending angle determination)]
    • Comparative bending analysis of peptaibols

Reference:

Chugh JK, Bruckner H, Wallace BA.
Biochemistry 2002, 41, 12934-12941.
Model for a helical bundle channel based on the high-resolution crystal structure of trichotoxin_A50E.

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