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(-) Description

Title :  STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, 10 STRUCTURES
 
Authors :  H. Gouda, H. Torigoe, A. Saito, M. Sato, Y. Arata, I. Shimada
Date :  28 Jun 96  (Deposition) - 11 Jan 97  (Release) - 24 Feb 09  (Revision)
Method :  SOLUTION NMR
Resolution :  NOT APPLICABLE
Chains :  NMR Structure  :  A  (10x)
Keywords :  Immunoglobulin-Binding Protein, Repeat, Transmembrane, Cell Wall, Signal, Immunoglobulin Binding Domain (Keyword Search: [Gene Ontology, PubMed, Web (Google))
 
Reference :  H. Gouda, H. Torigoe, A. Saito, M. Sato, Y. Arata, I. Shimada
Three-Dimensional Solution Structure Of The B Domain Of Staphylococcal Protein A: Comparisons Of The Solution And Crystal Structures.
Biochemistry V. 31 9665 1992
PubMed-ID: 1390743  |  Reference-DOI: 10.1021/BI00155A020
(for further references see the PDB file header)

(-) Compounds

Molecule 1 - STAPHYLOCOCCUS AUREUS PROTEIN A
    ChainsA
    EngineeredYES
    Expression SystemESCHERICHIA COLI
    Expression System PlasmidPPRAFW1
    Expression System Taxid562
    FragmentB DOMAIN
    GeneSYNTHETIC GENE
    Organism ScientificSTAPHYLOCOCCUS AUREUS
    Organism Taxid1280

 Structural Features

(-) Chains, Units

  
NMR Structure (10x)

Summary Information (see also Sequences/Alignments below)

(-) Ligands, Modified Residues, Ions  (0, 0)

(no "Ligand,Modified Residues,Ions" information available for 1BDC)

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 Sequence-Structure Mapping

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(-) Exons   (0, 0)

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(-) Sequences/Alignments

NMR Structure
   Reformat: Number of residues per line =  ('0' or empty: single-line sequence representation)
  Number of residues per labelling interval =   
  UniProt sequence: complete  aligned part    
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SAPs(SNPs) PROSITE motifs Exons
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Chain A from PDB  Type:PROTEIN  Length:60
 aligned with SPA_STAAU | P38507 from UniProtKB/Swiss-Prot  Length:508

    Alignment length:60
                                   220       230       240       250       260       270
            SPA_STAAU   211 KADNKFNKEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKA 270
               SCOP domains d1bdca_ A: Immunoglobulin-binding protein A modules          SCOP domains
               CATH domains 1bdcA00 A:1-60 Immunoglobulin FC, subunit C                  CATH domains
               Pfam domains ------------------------------------------------------------ Pfam domains
         Sec.struct. author .........hhhhhhhhhh.....hhhhhhhhhhhhh....hhhhhhhhhhhhhh..... Sec.struct. author
                 SAPs(SNPs) ------------------------------------------------------------ SAPs(SNPs)
                    PROSITE ------------------------------------------------------------ PROSITE
                 Transcript ------------------------------------------------------------ Transcript
                 1bdc A   1 TADNKFNKEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKA  60
                                    10        20        30        40        50        60

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 Classification and Annotation

(-) SCOP Domains  (1, 1)

NMR Structure

(-) CATH Domains  (1, 1)

NMR Structure

(-) Pfam Domains  (0, 0)

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(-) Gene Ontology  (6, 6)

NMR Structure(hide GO term definitions)
Chain A   (SPA_STAAU | P38507)
molecular function
    GO:0019864    IgG binding    Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype.
    GO:0019865    immunoglobulin binding    Interacting selectively and non-covalently with an immunoglobulin.
biological process
    GO:0009405    pathogenesis    The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
cellular component
    GO:0005618    cell wall    The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
    GO:0005576    extracellular region    The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
    GO:0016020    membrane    A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

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 Related Entries

(-) Entries Sharing at Least One Protein Chain (UniProt ID)

UniProtKB/Swiss-Prot
        SPA_STAAU | P385071bdd 1edi 1edj 1edk 1edl 1fc2 1h0t 1lp1 1q2n 1ss1 2jwd 2m5a 2spz 3mzw 4npd 4npe 4npf 4wwi 4y4y 4y5z 4zmd 4znc 5cbn 5cbo 5coc 5ewx 5h75 5h76 5h77 5h79 5h7a 5h7b 5h7c 5h7d 5x3f 5xby

(-) Related Entries Specified in the PDB File

1bdd