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(-) Description

Title :  WATER STRUCTURE OF A HYDROPHOBIC PROTEIN AT ATOMIC RESOLUTION. PENTAGON RINGS OF WATER MOLECULES IN CRYSTALS OF CRAMBIN
 
Authors :  W. A. Hendrickson, M. M. Teeter
Date :  30 Apr 81  (Deposition) - 28 Jul 81  (Release) - 11 Jul 12  (Revision)
Method :  X-RAY DIFFRACTION
Resolution :  1.50
Chains :  Asym./Biol. Unit :  A
Keywords :  Plant Seed Protein, Plant Protein (Keyword Search: [Gene Ontology, PubMed, Web (Google)] )
 
Reference :  M. M. Teeter
Water Structure Of A Hydrophobic Protein At Atomic Resolution: Pentagon Rings Of Water Molecules In Crystals O Crambin.
Proc. Natl. Acad. Sci. Usa V. 81 6014 1984
PubMed-ID: 16593516  |  Reference-DOI: 10.1073/PNAS.81.19.6014
(for further references see the PDB file header)

(-) Compounds

Molecule 1 - CRAMBIN
    Chains: A
    Engineered: YES
    Organism Scientific: CRAMBE HISPANICA SUBSP. ABYSSINICA
    Organism Taxid: 3721
    Strain: SUBSP. ABYSSINICA

 Structural Features

(-) Chains, Units

  1
Asymmetric/Biological Unit : A

Summary Information (see also Sequences/Alignments below)

(-) Ligands, Modified Residues, Ions  (0, 0)

(no "Ligand,Modified Residues,Ions" information available for 1CRN)

(-) Sites  (0, 0)

(no "Site" information available for 1CRN)

(-) SS Bonds  (3, 3)

Asymmetric/Biological Unit
No.Residues
1A:3 -A:40
2A:4 -A:32
3A:16 -A:26

(-) Cis Peptide Bonds  (0, 0)

(no "Cis Peptide Bond" information available for 1CRN)

 Sequence-Structure Mapping

(-) SAPs(SNPs)/Variants  (2, 2)

Asymmetric/Biological Unit (2, 2)
  dbSNPPDB
No.SourceVariant IDVariantUniProt IDStatusIDChainVariant
1UniProtVAR_CRAM_CRAAB_001 *P22SCRAM_CRAAB  ---  ---AP22S
2UniProtVAR_CRAM_CRAAB_002 *L25ICRAM_CRAAB  ---  ---AI25I
   * ID not provided by source
  SNP/SAP Summary Statistics (UniProtKB/Swiss-Prot)

(-) PROSITE Motifs  (1, 1)

Asymmetric/Biological Unit (1, 1)
 PROSITEUniProtKBPDB
No.IDACDescriptionIDLocationCountLocation
1THIONINPS00271 Plant thionins signature.CRAM_CRAAB3-16  1A:3-16

(-) Exons   (0, 0)

(no "Exon" information available for 1CRN)

(-) Sequences/Alignments

Asymmetric/Biological Unit
   Reformat: Number of residues per line =  ('0' or empty: single-line sequence representation)
  Number of residues per labelling interval =   
  UniProt sequence: complete  aligned part    
   Show mapping: SCOP domains CATH domains Pfam domains Secondary structure (by author)
SAPs(SNPs) PROSITE motifs Exons
(details for a mapped element are shown in a popup box when the mouse pointer rests over it) 
Chain A from PDB  Type:PROTEIN  Length:46
 aligned with CRAM_CRAAB | P01542 from UniProtKB/Swiss-Prot  Length:46

    Alignment length:46
                                    10        20        30        40      
            CRAM_CRAAB    1 TTCCPSIVARSNFNVCRLPGTPEALCATYTGCIIIPGATCPGDYAN 46
               SCOP domains d1crna_ A: Crambin                             SCOP domains
               CATH domains 1crnA00 A:1-46                                 CATH domains
               Pfam domains ---------------------------------------------- Pfam domains
         Sec.struct. author eeee..hhhhhhhhhhhhh...hhhhhhhh.eeee........... Sec.struct. author
                 SAPs(SNPs) ---------------------S--I--------------------- SAPs(SNPs)
                    PROSITE --THIONIN       ------------------------------ PROSITE
                 Transcript ---------------------------------------------- Transcript
                  1crn A  1 TTCCPSIVARSNFNVCRLPGTPEAICATYTGCIIIPGATCPGDYAN 46
                                    10        20        30        40
   Legend:   → Mismatch (orange background)
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  x → Chemical Group (purple background, 'x', labelled with number + name, e.g. ACE or NH2)
  extra numbering lines below/above indicate numbering irregularities and modified residue names etc., number ends below/above '|'

 Classification and Annotation

(-) SCOP Domains  (1, 1)

Asymmetric/Biological Unit
(-)
Class: Small proteins (3458)

(-) CATH Domains  (1, 1)

Asymmetric/Biological Unit
(-)
Class: Alpha Beta (26913)

(-) Pfam Domains  (0, 0)

(no "Pfam Domain" information available for 1CRN)

(-) Gene Ontology  (2, 2)

Asymmetric/Biological Unit(hide GO term definitions)
Chain A   (CRAM_CRAAB | P01542)
biological process
    GO:0006952    defense response    Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
cellular component
    GO:0005576    extracellular region    The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

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 Related Entries

(-) Entries Sharing at Least One Protein Chain (UniProt ID)

UniProtKB/Swiss-Prot
        CRAM_CRAAB | P01542: 1ab1 1cbn 1ccm 1ccn 1cnr 1cxr 1ejg 1jxt 1jxu 1jxw 1jxx 1jxy 1yv8 1yva 2eya 2eyb 2eyc 2eyd 2fd7 2fd9 3nir 3u7t 3ue7 4fc1

(-) Related Entries Specified in the PDB File

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